Tandem Mass Spectroscopy

1. Tandem mass spectroscopy combines which of the following devices?

a) Mass spectrometer and gas-solid chromatograph

b) Mass spectrometer and gas-liquid chromatograph

c) Mass spectrometer and gas chromatograph

d) Mass spectrometer and mass spectrometer

Answer: d

2. In tandem spectroscopy, the first stage sepatation device is a mass spectrometer.

a) True

b) False

Answer: a

3. Which of the following is used to separate a single mass that is characteristic of a given analyte in a mixture?

a) First mass spectrometer

b) Second mass spectrometer

c) Filter

d) Precursor

Answer: a

4. The mass-selected ions are activated in which of the following ways that causes them to fall apart to produce product ions?

a) Collisional activation

b) Evaporational activation

c) Inert gas activation

d) Thermal activation

Answer: a

5. The final MS/MS spectrum consists only of product ions from the selected precursor.

a) True

b) False

Answer: a

6. In reverse-geometry mass spectrometer which of the following precedes the electric sector?

a) Nebulizer

b) Orifice

c) Magnetic sector

d) Mass spectrometer

Answer: c

7. A magnetic sector alone can be used as a mass spectrometer, with roughly _____ resolution.

a) Low

b) High

c) Unit

d) Infinite

Answer: c

8. What does the acronym ‘MIKES’ stand for?

a) Mass-analysed ion kinetic energy spectrometer

b) Mass-based induced kinetic energy spectrometer

c) Mass invasive kinetic electric spectrometer

d) Mass-analyser in kinetic energy-type spectrometer

Answer: a

9. In MIKES experiments which of the following are measured?

a) Product ions

b) Product ion kinetic energies

c) Product ions mass to charge ratio

d) Product ions masses

Answer: b

10. All ions with the same number of charges will have __________

a) Same kinetic energy

b) Different kinetic energies

c) Same mass

d) Different mass

Answer: a

11. A tandem mass spectrometer has which of the following analysers?

a) Time of flight mass analyser

b) Magnetic deflection analyser

c) Radiofrequency analyser

d) Quadrupole analyser

Answer: a

12. Which of the following filters are used in tandem spectrometer?

a) Quadrupole mass filter

b) Low energy filter

c) High energy filter

d) Time of flight mass filter

Answer: a

13. B/E scan is which of the following scans?

a) Product ion scan

b) Precursor ion scan

c) Mass scan

d) Charge scan

Answer: a

14. Which of the following is located in the region between two analysers?

a) Nebuliser

b) Collision cell

c) Filter

d) Vacuum chamber

Answer: b